Прием по комбинированной схеме, вначале - интраназально пипеткой от 1 до 4 капель, затем внутрь от 0,5 мл до 4 мл. Максимальное количество приема внутрь для детей - 8, для взрослых - 10.

Высшая суточная доза: 4 мл.

Высшая разовая доза: 3 мл.

","

Заложенность носа, кожный зуд, кашель, аллергические реакции.

","

Возраст до 3 лет, обострение психических заболеваний, активный туберкулез, беременность и лактация, коллагенозы, лихорадка с температурой выше 38⁰С, индивидуальная непереносимость.

","specialInstructions","

Не рекомендуется назначение иных иммуномодуляторов в течение 1 месяца до начала, во время и спустя 3 месяца после окончания приема препарата.

","interactions","

Случаи передозировки не описаны.

Лечение симптоматическое.

","overdose","actionMechanism","pharmacodynamic","

Содержит комплекс антигенов условно-патогенных бактерий Staphylococcus aureus+Klebsiella pneumoniae+Proteus vulgaris+Escherichia coli F-147, за счет чего стимулирует выработку антител, в том числе к иным видам, благодаря перекрестной протективной активности.

Активирует активность макрофагов, усиливая процессы фагоцитоза. Увеличивает количество и стимулирует активность Т-лимфоцитов. Регулирует синтез имунноглобулинов, увеличивая количество IgG, IgA, slgA, одновременно снижая фракцию lgE. В результате снижает частоту развития и продолжительность острых инфекций, уменьшает вероятность обострения хронических болезней, снижает объем приема лекарственных средств.

","pharmacokinetic","

Не описана.

","pregnancy","

Рекомендации по FDA - категория С. Противопоказан при беременности и в период лактации.

","fertility","precautions","

Гиперчувствительность.

","indications","

Применяется для иммунотерапии и имуннопрофилактики взрослых и детей с 3-летнего возраста: воспалительных заболеваний органов дыхания, респираторных инфекций, аллергических заболеваний - бронхиальной астмы, атопического дерматита, обструктивного бронхита, дисбактериоза.

Используется для профилактики респираторных инфекций у людей, болеющих ОРЗ чаще четырех раз в год.

","drivingInstructions","icd10",[197,209,216,222,228,234,240,246,252,258,264,270,276,282,288,294,300,306,312,318,324,330,336],{"_198":199,"_164":200,"_162":201,"_202":199,"_159":203,"_5":204,"_205":206,"_207":208},"drugGeotarID","A49.8","Other bacterial infections of unspecified site","Другие бактериальные инфекции неуточненной локализации","drugICD10CodeShort","QTQ5Ljg","DrugICD10","code","I(A00-B99).A30-A49.A49.8","level","4",{"_198":210,"_164":211,"_162":212,"_202":210,"_159":213,"_5":204,"_205":214,"_207":215},"B00","Herpesviral [herpes simplex] infections","Инфекции, вызванные вирусом герпеса [herpes simplex]","QjAw","I(A00-B99).B00-B09.B00","3",{"_198":217,"_164":218,"_162":219,"_202":217,"_159":220,"_5":204,"_205":221,"_207":208},"J15.9","Bacterial pneumonia, unspecified","Бактериальная пневмония неуточненная","SjE1Ljk","X(J00-J99).J09-J18.J15.9",{"_198":223,"_164":224,"_162":225,"_202":223,"_159":226,"_5":204,"_205":227,"_207":208},"J30.1","Allergic rhinitis due to pollen","Аллергический ринит, вызванный пыльцой растений","SjMwLjE","X(J00-J99).J30-J39.J30.1",{"_198":229,"_164":230,"_162":231,"_202":229,"_159":232,"_5":204,"_205":233,"_207":208},"J30.2","Other seasonal allergic rhinitis","Другие сезонные аллергические риниты","SjMwLjI","X(J00-J99).J30-J39.J30.2",{"_198":235,"_164":236,"_162":237,"_202":235,"_159":238,"_5":204,"_205":239,"_207":208},"J30.4","Allergic rhinitis, unspecified","Аллергический ринит неуточненный","SjMwLjQ","X(J00-J99).J30-J39.J30.4",{"_198":241,"_164":242,"_162":243,"_202":241,"_159":244,"_5":204,"_205":245,"_207":215},"J31","Chronic rhinitis, nasopharyngitis and pharyngitis","Хронический ринит, назофарингит и фарингит","SjMx","X(J00-J99).J30-J39.J31",{"_198":247,"_164":248,"_162":249,"_202":247,"_159":250,"_5":204,"_205":251,"_207":215},"J32","Chronic sinusitis","Хронический синусит","SjMy","X(J00-J99).J30-J39.J32",{"_198":253,"_164":254,"_162":255,"_202":253,"_159":256,"_5":204,"_205":257,"_207":208},"J35.0","Chronic tonsillitis","Хронический тонзиллит","SjM1LjA","X(J00-J99).J30-J39.J35.0",{"_198":259,"_164":260,"_162":261,"_202":259,"_159":262,"_5":204,"_205":263,"_207":215},"J37","Chronic laryngitis and laryngotracheitis","Хронический ларингит и ларинготрахеит","SjM3","X(J00-J99).J30-J39.J37",{"_198":265,"_164":266,"_162":267,"_202":265,"_159":268,"_5":204,"_205":269,"_207":215},"J40","Bronchitis, not specified as acute or chronic","Бронхит, не уточненный как острый или хронический","SjQw","X(J00-J99).J40-J47.J40",{"_198":271,"_164":272,"_162":273,"_202":271,"_159":274,"_5":204,"_205":275,"_207":215},"J42","Unspecified chronic bronchitis","Хронический бронхит неуточненный","SjQy","X(J00-J99).J40-J47.J42",{"_198":277,"_164":278,"_162":279,"_202":277,"_159":280,"_5":204,"_205":281,"_207":215},"J44","Other chronic obstructive pulmonary disease","Другая хроническая обструктивная легочная болезнь","SjQ0","X(J00-J99).J40-J47.J44",{"_198":283,"_164":284,"_162":285,"_202":283,"_159":286,"_5":204,"_205":287,"_207":208},"J44.1","Chronic obstructive pulmonary disease with acute exacerbation, unspecified","Хроническая обструктивная легочная болезнь с обострением неуточненная","SjQ0LjE","X(J00-J99).J40-J47.J44.1",{"_198":289,"_164":290,"_162":291,"_202":289,"_159":292,"_5":204,"_205":293,"_207":208},"J44.9","Chronic obstructive pulmonary disease, unspecified","Хроническая обструктивная легочная болезнь неуточненная","SjQ0Ljk","X(J00-J99).J40-J47.J44.9",{"_198":295,"_164":296,"_162":297,"_202":295,"_159":298,"_5":204,"_205":299,"_207":208},"J45.0","Predominantly allergic asthma","Астма с преобладанием аллергического компонента","SjQ1LjA","X(J00-J99).J40-J47.J45.0",{"_198":301,"_164":302,"_162":303,"_202":301,"_159":304,"_5":204,"_205":305,"_207":208},"J45.9","Asthma, unspecified","Астма неуточненная","SjQ1Ljk","X(J00-J99).J40-J47.J45.9",{"_198":307,"_164":308,"_162":309,"_202":307,"_159":310,"_5":204,"_205":311,"_207":215},"J85","Abscess of lung and mediastinum","Абсцесс легкого и средостения","Sjg1","X(J00-J99).J85-J86.J85",{"_198":313,"_164":314,"_162":315,"_202":313,"_159":316,"_5":204,"_205":317,"_207":215},"L02","Cutaneous abscess, furuncle and carbuncle","Абсцесс кожи, фурункул и карбункул","TDAy","XII(L00-L99).L00-L08.L02",{"_198":319,"_164":320,"_162":321,"_202":319,"_159":322,"_5":204,"_205":323,"_207":208},"L08.0","Pyoderma","Пиодермия","TDA4LjA","XII(L00-L99).L00-L08.L08.0",{"_198":325,"_164":326,"_162":327,"_202":325,"_159":328,"_5":204,"_205":329,"_207":208},"L20.8","Other atopic dermatitis","Другие атопические дерматиты","TDIwLjg","XII(L00-L99).L20-L30.L20.8",{"_198":331,"_164":332,"_162":333,"_202":331,"_159":334,"_5":204,"_205":335,"_207":208},"L20.9","Atopic dermatitis, unspecified","Атопический дерматит неуточненный","TDIwLjk","XII(L00-L99).L20-L30.L20.9",{"_198":337,"_164":338,"_162":339,"_202":337,"_159":340,"_5":204,"_205":341,"_207":208},"L73.2","Hidradenitis suppurativa","Гидраденит гнойный","TDczLjI","XII(L00-L99).L60-L75.L73.2","atc",[344,350],{"_198":345,"_164":346,"_162":347,"_159":348,"_5":349,"_205":348,"_207":215},"J.07.A","Bacterial Vaccines","Вакцины для профилактики бактериальных инфекций","J07A","DrugATC",{"_198":351,"_164":352,"_162":353,"_159":354,"_5":349,"_205":354,"_207":208},"L.03.A.X","Other Immunostimulants","Другие иммуностимуляторы","L03AX","contraindicationsList","precautionsList","adverseEffectList",[],"pharmGroupList","6.3.4 Другие иммуномодуляторы","substanceType","Непатентованное международное наименование","structure","[?] ","image",{"_40":367,"_368":10},"/images/substance-placeholder.jpg","isPlaceholder","esklp",{"_371":372,"_373":-5},"esklpList",[],"isInnVital","aggregatedEsklpGroups",[],"entityId","https://www.lsgeotar.ru/substances/staphylococcus-aureusklebsiella-pneumoniaeproteus-vulgarisescherichia-coli-f-147-AALy/interactions","substanceInteractions",{"_42":380,"_386":126,"_387":388,"_389":390},{"_381":382,"_383":72,"_384":126,"_385":-5},"query","","pageSize","page","filters","total","countedSignificances",[],"interactionList",[],"pages/PagesLayout","actionData","errors"]

Антигены условно-патогенных микроорганизмов ([Staphylococcus aureus+Klebsiella pneumoniae+Proteus vulgaris+Escherichia coli F-147])