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Остеоартроз: внутрисуставно.

Заболевания глаз: в нижний конъюнктивальный мешок пораженного глаза.

","

Системные реакции: аллергические реакции.

Местные реакции: боль, покраснение, отек тканей.

","

Инфекционные поражения кожи и тканей в области сустава;
выраженный синовит;
детский возраст (нет данных по эффективности и безопасности);
повышенная чувствительность.

","specialInstructions","interactions","

Лекарственное взаимодействие гликопротеина сывороточного с другими лекарственными препаратами не описано.

","overdose","

Ввиду низкой концентрации препарата и его незначительной абсорбции возможность передозировки маловероятна.

","actionMechanism","pharmacodynamic","

Гликопротеин сывороточный тормозит процесс дегенерации и стимулирует регенерацию хрящевой ткани при повреждении. Стимулирует рост культур фибробластов, пролиферативную активность лимфоцитов, препятствует развитию воспалительного процесса, обладает антиоксидантными свойствами, предупреждает повреждение мембранных структур клеток при различных патологических состояниях. Усиливает адгезивные взаимодействия клеток мезенхимного происхождения. При повреждении суставного хряща стимулирует накопление хондробластов, их дифференцировку в хондроциты, заполнение хондроцитами области повреждения, восстановление суставной поверхности и подвижности сустава. Усиливает выработку хондроцитами хрящевого матрикса, коллагена II типа, протеогликанов. Способствует упорядочиванию структуры матрикса.

Устраняет или уменьшает болевой синдром.

Гликопротеин сывороточный стимулирует репаративные процессы в роговице глаза, способствуя активации фибробластических элементов, препятствует развитию воспалительного процесса, разрастанию рубцовой ткани, врастанию сосудов в роговицу.

В случае ожогового поражения глаз лечебный эффект гликопротеина сывороточного отмечается к 14-м суткам и сопровождается значительной пролиферацией фибробластических элементов, инфильтрующих травмированную роговичную ткань, при этом векторная направленность пролиферирующих клеток имитирует исходную морфологическую структуру роговицы.

Гликопротеин сывороточный нетоксичен, не оказывает неблагоприятного воздействия на ткани глаза и организм в целом, не вызывает аллергической реакции ткани при длительном применении.

","pharmacokinetic","

Данные о фармакокинетике препарата не предоставлены.

","pregnancy","

Данных о применении препарата у беременных и в период лактации нет.

","fertility","precautions","indications","

Остеоартроз крупных суставов;

кератопатии;

эрозии роговицы;

кератиты (в т.ч. герпетический и аденовирусный);

ожоги глаз;

проникающие ранения роговиц

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Гликопротеин сывороточный (Serum glycoprotein)