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Наружно в виде геля, наносится на пораженные участки 2-3 раза в сутки в течение 2-3 недель.

","

Аллергические реакции.

","Инфицированные трофические язвы, индивидуальная непереносимость, детский возраст до 3-х лет.

","specialInstructions","

Средство не предназначено для интравагинального и ректального введения, также не применяется в офтальмологии.

","interactions","

Клинически значимых взаимодействий не описано.

","overdose","

Случаи передозировки не описаны.

Лечение симптоматическое.

","actionMechanism","pharmacodynamic","

Комбинированное средство для местного применения.

Гепарин натрия

Антикоагулянт прямого действия. За счет активации антитромбина III ускоряет его противосвертывающее действие. Блокирует синтез тромбина, снижает агрегацию тромбоцитов. Снижает активность гиалуронидазы. Предотвращает образование и способствует рассасыванию имеющихся тромбов, улучшает местный кровоток, обладает противовоспалительным и противоотечным действием.

Декспантенол

После всасывания в кожу трансформируется в пантотеновую кислоту - витамин группы В₅. Пантотеновая кислота является компонентом коэнзима А, который принимает участие в обменных процессах, за счет чего улучшает процессы регенерации и эпителизации поврежденных участков кожи.

Троксерутин

Ангиопротектор из группы биофлавоноидов. Блокирует венодилатирующее действие ацетилхолина, брадикинина и гистамина. Снижает проницаемость и ломкость капилляров, обладает слабым антиагрегантным действием. Улучшает трофику и снижает отек ткани, связанный с венозной недостаточностью.

","pharmacokinetic","Препарат для местного применения, системного действия на организм не оказывает.

","pregnancy","Рекомендации по FDA - категория В. Применяется во время беременности и лактации.

","fertility","precautions","Гиперчувствительность.

","indications","Применяется для лечения травм мягких тканей: растяжений, вывихов, гематом. Используется при отечно-болевом синдроме вследствие венозной недостаточности нижних конечностей, а также для усиления эпителизации трофических язв.

","drivingInstructions","icd10",[178,190,196,203,209,215,221,227],{"_179":180,"_144":181,"_142":182,"_183":180,"_138":184,"_140":185,"_186":187,"_188":189},"drugGeotarID","I80","Phlebitis and thrombophlebitis","Флебит и тромбофлебит","drugICD10CodeShort","STgw","DrugICD10","code","IX(I00-I99).I80-I89.I80","level","3",{"_179":191,"_144":192,"_142":193,"_183":191,"_138":194,"_140":185,"_186":195,"_188":189},"I83","Varicose veins of lower extremities","Варикозное расширение вен нижних конечностей","STgz","IX(I00-I99).I80-I89.I83",{"_179":197,"_144":198,"_142":199,"_183":197,"_138":200,"_140":185,"_186":201,"_188":202},"I83.2","Varicose veins of lower extremities with both ulcer and inflammation","Варикозное расширение вен нижних конечностей с язвой и воспалением","STgzLjI","IX(I00-I99).I80-I89.I83.2","4",{"_179":204,"_144":205,"_142":206,"_183":204,"_138":207,"_140":185,"_186":208,"_188":202},"I87.0","Postthrombotic syndrome","Посттромботический синдром","STg3LjA","IX(I00-I99).I80-I89.I87.0",{"_179":210,"_144":211,"_142":212,"_183":210,"_138":213,"_140":185,"_186":214,"_188":202},"I87.2","Venous insufficiency (chronic)(peripheral)","Венозная недостаточность (хроническая) (периферическая)","STg3LjI","IX(I00-I99).I80-I89.I87.2",{"_179":216,"_144":217,"_142":218,"_183":216,"_138":219,"_140":185,"_186":220,"_188":189},"I89","Other noninfective disorders of lymphatic vessels and lymph nodes","Другие неинфекционные болезни лимфатических сосудов и лимфатических узлов","STg5","IX(I00-I99).I80-I89.I89",{"_179":222,"_144":223,"_142":224,"_183":222,"_138":225,"_140":185,"_186":226,"_188":202},"T14.0","Superficial injury of unspecified body region","Поверхностная травма неуточненной области тела","VDE0LjA","XIX(S00-T98).T08-T14.T14.0",{"_179":228,"_144":229,"_142":230,"_183":228,"_138":231,"_140":185,"_186":232,"_188":202},"T14.3","Dislocation, sprain and strain of unspecified body region","Вывих, растяжение и перенапряжение капсульно-связочного аппаратата сустава неуточненной области тела","VDE0LjM","XIX(S00-T98).T08-T14.T14.3","atc",[235,241],{"_179":236,"_144":237,"_142":238,"_138":239,"_140":240,"_186":239,"_188":202},"C.05.B.A","Heparins Or Heparinoids For Topical Use","Гепарины или гепариноиды для местного применения","C05BA","DrugATC",{"_179":242,"_144":243,"_142":244,"_138":245,"_140":240,"_186":245,"_188":246},"C.05.B.A.53","Heparin, Combinations","Гепаринт в комбинации с другими средствами","C05BA53","5","contraindicationsList",[249],{"_142":250,"_138":251,"_140":252,"_179":251},"Детский возраст до 3 лет","chld_3","DrugPatientStatus","precautionsList","adverseEffectList",[],"pharmGroupList","

11.5.2 Ангиопротекторы и корректоры микроциркуляции
14 Регенеранты и репаранты
2.2 Антикоагулянты

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Гепарин натрия + Декспантенол + Троксерутин (Heparinum natrium + Dexpanthenolum + Troxerutinum)