[{"_1":2,"_272":-5,"_273":-5},"loaderData",{"_3":4,"_132":133,"_258":259,"_271":-5},"root",{"_5":6,"_97":98,"_117":118},"appConfig",{"_7":8,"_9":10,"_11":12,"_13":14,"_15":16,"_17":18,"_19":20,"_47":48,"_49":50,"_59":60,"_61":62},"lsEnabled",true,"salesEmail","sale@lsgeotar.ru","supportEmail","support@lsgeotar.ru","infoEmail","info@lsgeotar.ru","primaryPhoneNumber","8 (800) 234-13-74","secondaryPhoneNumber","+7 (985) 750-03-09","medBase",{"_21":22,"_23":-5,"_24":25,"_26":27,"_28":29,"_30":31,"_32":33,"_34":35,"_36":37,"_46":39},"baseUrl","https://medbase.ru","ssr","loginIframeUrl","https://medbase.ru/bind_external_user.html","userProfileUrl","https://medbase.ru/cur_user/general.html","aboutUrl","/pages/about.html","bookUrl","/book/{{id}}.html","readerUrl","/doc/{{id}}-0001/0001.html","selfDomain","https://www.lsgeotar.ru","payment",{"_38":39,"_40":41},"url","https://medbase.ru/pages/buy_acc.html","params",{"_42":43,"_44":45},"tab","LS-DDI","XFrom","lsgeotar","buySubscriptionUrl","geotarCifraUrl","https://cifra.geotar.ru","analytics",{"_51":52,"_55":56},"yandexMetrika",{"_53":54},"counterId","35376590","googleAnalytics",{"_57":58},"measurementId","G-FRG71EZEZG","isDevHost",false,"quotas",{"_63":64,"_86":87,"_91":92},"anonymous",{"_65":66,"_71":72},"limits",{"_67":68,"_69":70},"medication-check.input.max",2,"substance.interactions.max",3,"features",{"_73":60,"_74":60,"_75":60,"_76":60,"_77":60,"_78":8,"_79":60,"_80":8,"_81":60,"_82":60,"_83":60,"_84":60,"_85":60},"medication-check.results.export","substance.interactions.filter","substance.interactions.extended-interaction-info","entity.instructions.view","esklp.substance.info","meddra","meddra.substance.info","meddra.medication-check.adverse-effects","meddra.medication-check.adverse-effects.content","clinrecs","clinrecs.clinrec.medications","clinrecs.substance.clinrecs","clinrecs.medication-check","registered",{"_65":88,"_71":90},{"_67":89,"_69":89},5,{"_73":60,"_74":8,"_75":60,"_76":8,"_77":60,"_78":8,"_79":60,"_80":8,"_81":60,"_82":60,"_83":60,"_84":60,"_85":60},"pro",{"_65":93,"_71":96},{"_67":94,"_69":95},50,20000,{"_73":8,"_74":8,"_75":60,"_76":8,"_77":8,"_78":8,"_79":8,"_80":8,"_81":8,"_82":60,"_83":60,"_84":60,"_85":60},"userInfo",{"_99":60,"_100":-5,"_101":-5,"_102":63,"_103":63,"_104":105,"_61":106,"_109":110},"isAuthenticated","firstName","lastName","accessType","userName","roles",[],{"_65":107,"_71":108},{"_67":68,"_69":70},{"_73":60,"_74":60,"_75":60,"_76":60,"_77":60,"_78":8,"_79":60,"_80":8,"_81":60,"_82":60,"_83":60,"_84":60,"_85":60},"bffQuotas",{"_111":112,"_113":68,"_114":70,"_115":112,"_116":112},"instructions.view",0,"interactions.calculator.input.max","interactions.list.results.max","inn.dosages.view","interactions.calculator.report.download","userProfile",{"_119":120},"settings",{"_121":122,"_124":128,"_130":131},"layout",{"_123":60,"_124":125,"_126":127},"tablePinPrimaryColumn","contraindications","table","adverseEffects","soc",{"_129":60},"hidePregnancyAndAge","dontShowAgain",{},"substance",{"_134":135,"_256":139,"_38":257},"data",{"_136":137,"_138":139,"_140":141,"_142":143,"_144":145,"_146":147,"_148":-5,"_149":150,"_151":112,"_152":-7,"_153":154,"_126":155,"_124":156,"_157":158,"_159":160,"_161":162,"_163":-7,"_164":165,"_166":167,"_168":169,"_170":-7,"_171":172,"_173":174,"_175":-7,"_176":177,"_221":222,"_230":231,"_236":-7,"_237":238,"_239":240,"_241":242,"_243":244,"_245":246,"_249":250,"_254":255},"itemClass","InnCard","id","ABiR","type","DrugINN","name","Гепарин натрия + [аллантоин + декспантенол]","internationalName","Heparin sodium + [allantoin + dexpanthenol]","geotarId","2328","drugBankId","docAttachments",[],"clinRecCount","description","application","

Применяется наружно 2-3 раза в сутки столбиком по 4-5 см, не втирая, в течение 10-14 дней.

Высшая суточная доза: 15-20 см.

Высшая разовая доза: 5 см.

","

Аллергические реакции.

","

Нарушение целостности кожных покровов, индивидуальная непереносимость, детский возраст до 3-х лет.

","specialInstructions","

При лечении трофических язв мазь наносится столбиком в виде кольца шириной до 4 см.

При заболеваниях вен применяются повязки с мазью.

","interactions","

Клинически значимых взаимодействий не описано.

","overdose","

Случаи передозировки не описаны.

Лечение симптоматическое.

","actionMechanism","pharmacodynamic","

Комбинированное средство для местного применения.

Гепарин натрия

Антикоагулянт прямого действия. За счет активации антитромбина III ускоряет его противосвертывающее действие. Блокирует синтез тромбина, снижает агрегацию тромбоцитов. Снижает активность гиалуронидазы. Предотвращает образование и способствует рассасыванию имеющихся тромбов, улучшает местный кровоток, обладает противовоспалительным и противоотечным действием.

Аллантоин

Способствует регенерационным процессам, усиливает пролиферацию клеток, улучшает обменные процессы в тканях.

Декспантенол

Ускоряет процессы эпителизации тканей, способствует ускорению всасывания гепарина.

","pharmacokinetic","

Препарат для местного применения, системного действия на организм не оказывает.

Период полувыведения из кожи и эпидермиса составляет 1-1,5 часа.

","pregnancy","

Рекомендации по FDA - категория В. Применяется во время беременности и лактации.

","fertility","precautions","

Тромбоцитопения, гиперчувствительность.

","indications","

Применяется для лечения сосудистых заболеваний нижних конечностей: тромбофлебита, тромбоза, варикозного расширения поверхностных вен. Используется при спортивных травмах, воспалительных инфильтратах, тендовагинитах.

","drivingInstructions","icd10",[178,190,196,203,209,215],{"_179":180,"_144":181,"_142":182,"_183":180,"_138":184,"_140":185,"_186":187,"_188":189},"drugGeotarID","I80","Phlebitis and thrombophlebitis","Флебит и тромбофлебит","drugICD10CodeShort","STgw","DrugICD10","code","IX(I00-I99).I80-I89.I80","level","3",{"_179":191,"_144":192,"_142":193,"_183":191,"_138":194,"_140":185,"_186":195,"_188":189},"I83","Varicose veins of lower extremities","Варикозное расширение вен нижних конечностей","STgz","IX(I00-I99).I80-I89.I83",{"_179":197,"_144":198,"_142":199,"_183":197,"_138":200,"_140":185,"_186":201,"_188":202},"I83.2","Varicose veins of lower extremities with both ulcer and inflammation","Варикозное расширение вен нижних конечностей с язвой и воспалением","STgzLjI","IX(I00-I99).I80-I89.I83.2","4",{"_179":204,"_144":205,"_142":206,"_183":204,"_138":207,"_140":185,"_186":208,"_188":202},"M65","Synovitis and tenosynovitis","Синовиты и теносиновиты","TTY1","XIII(M00-M99).M60-M79.M65-M68.M65",{"_179":210,"_144":211,"_142":212,"_183":210,"_138":213,"_140":185,"_186":214,"_188":189},"T14","Injury of unspecified body region","Травма неуточненной локализации","VDE0","XIX(S00-T98).T08-T14.T14",{"_179":216,"_144":217,"_142":218,"_183":216,"_138":219,"_140":185,"_186":220,"_188":202},"T14.0","Superficial injury of unspecified body region","Поверхностная травма неуточненной области тела","VDE0LjA","XIX(S00-T98).T08-T14.T14.0","atc",[223],{"_179":224,"_144":225,"_142":226,"_138":227,"_140":228,"_186":227,"_188":229},"C.05.B.A.53","Heparin, Combinations","Гепаринт в комбинации с другими средствами","C05BA53","DrugATC","5","contraindicationsList",[232],{"_142":233,"_138":234,"_140":235,"_179":234},"Детский возраст до 3 лет","chld_3","DrugPatientStatus","precautionsList","adverseEffectList",[],"pharmGroupList","

10 Ненаркотические анальгетики, включая нестероидные и другие противовоспалительные средства
14 Регенеранты и репаранты
2.2 Антикоагулянты

","substanceType","Непатентованное международное наименование","structure","[?] ","image",{"_38":247,"_248":8},"/images/substance-placeholder.jpg","isPlaceholder","esklp",{"_251":252,"_253":-5},"esklpList",[],"isInnVital","aggregatedEsklpGroups",[],"entityId","https://www.lsgeotar.ru/substances/heparin-sodium-allantoin-dexpanthenol-ABiR/interactions","substanceInteractions",{"_40":260,"_266":112,"_267":268,"_269":270},{"_261":262,"_263":70,"_264":112,"_265":-5},"query","","pageSize","page","filters","total","countedSignificances",[],"interactionList",[],"pages/PagesLayout","actionData","errors"]

Гепарин натрия + [аллантоин + декспантенол] (Heparin sodium + [allantoin + dexpanthenol])