[{"_1":2,"_296":-5,"_297":-5},"loaderData",{"_3":4,"_132":133,"_282":283,"_295":-5},"root",{"_5":6,"_97":98,"_117":118},"appConfig",{"_7":8,"_9":10,"_11":12,"_13":14,"_15":16,"_17":18,"_19":20,"_47":48,"_49":50,"_59":60,"_61":62},"lsEnabled",true,"salesEmail","sale@lsgeotar.ru","supportEmail","support@lsgeotar.ru","infoEmail","info@lsgeotar.ru","primaryPhoneNumber","8 (800) 234-13-74","secondaryPhoneNumber","+7 (985) 750-03-09","medBase",{"_21":22,"_23":-5,"_24":25,"_26":27,"_28":29,"_30":31,"_32":33,"_34":35,"_36":37,"_46":39},"baseUrl","https://medbase.ru","ssr","loginIframeUrl","https://medbase.ru/bind_external_user.html","userProfileUrl","https://medbase.ru/cur_user/general.html","aboutUrl","/pages/about.html","bookUrl","/book/{{id}}.html","readerUrl","/doc/{{id}}-0001/0001.html","selfDomain","https://www.lsgeotar.ru","payment",{"_38":39,"_40":41},"url","https://medbase.ru/pages/buy_acc.html","params",{"_42":43,"_44":45},"tab","LS-DDI","XFrom","lsgeotar","buySubscriptionUrl","geotarCifraUrl","https://cifra.geotar.ru","analytics",{"_51":52,"_55":56},"yandexMetrika",{"_53":54},"counterId","35376590","googleAnalytics",{"_57":58},"measurementId","G-FRG71EZEZG","isDevHost",false,"quotas",{"_63":64,"_86":87,"_91":92},"anonymous",{"_65":66,"_71":72},"limits",{"_67":68,"_69":70},"medication-check.input.max",2,"substance.interactions.max",3,"features",{"_73":60,"_74":60,"_75":60,"_76":60,"_77":60,"_78":8,"_79":60,"_80":8,"_81":60,"_82":60,"_83":60,"_84":60,"_85":60},"medication-check.results.export","substance.interactions.filter","substance.interactions.extended-interaction-info","entity.instructions.view","esklp.substance.info","meddra","meddra.substance.info","meddra.medication-check.adverse-effects","meddra.medication-check.adverse-effects.content","clinrecs","clinrecs.clinrec.medications","clinrecs.substance.clinrecs","clinrecs.medication-check","registered",{"_65":88,"_71":90},{"_67":89,"_69":89},5,{"_73":60,"_74":8,"_75":60,"_76":8,"_77":60,"_78":8,"_79":60,"_80":8,"_81":60,"_82":60,"_83":60,"_84":60,"_85":60},"pro",{"_65":93,"_71":96},{"_67":94,"_69":95},50,20000,{"_73":8,"_74":8,"_75":60,"_76":8,"_77":8,"_78":8,"_79":8,"_80":8,"_81":8,"_82":60,"_83":60,"_84":60,"_85":60},"userInfo",{"_99":60,"_100":-5,"_101":-5,"_102":63,"_103":63,"_104":105,"_61":106,"_109":110},"isAuthenticated","firstName","lastName","accessType","userName","roles",[],{"_65":107,"_71":108},{"_67":68,"_69":70},{"_73":60,"_74":60,"_75":60,"_76":60,"_77":60,"_78":8,"_79":60,"_80":8,"_81":60,"_82":60,"_83":60,"_84":60,"_85":60},"bffQuotas",{"_111":112,"_113":68,"_114":70,"_115":112,"_116":112},"instructions.view",0,"interactions.calculator.input.max","interactions.list.results.max","inn.dosages.view","interactions.calculator.report.download","userProfile",{"_119":120},"settings",{"_121":122,"_124":128,"_130":131},"layout",{"_123":60,"_124":125,"_126":127},"tablePinPrimaryColumn","contraindications","table","adverseEffects","soc",{"_129":60},"hidePregnancyAndAge","dontShowAgain",{},"substance",{"_134":135,"_280":139,"_38":281},"data",{"_136":137,"_138":139,"_140":141,"_142":143,"_144":145,"_146":147,"_148":-5,"_149":150,"_151":112,"_152":-7,"_153":154,"_126":155,"_124":156,"_157":158,"_159":160,"_161":162,"_163":-7,"_164":165,"_166":167,"_168":169,"_170":-7,"_171":172,"_173":174,"_175":-7,"_176":177,"_246":247,"_254":255,"_260":-7,"_261":262,"_263":264,"_265":266,"_267":268,"_269":270,"_273":274,"_278":279},"itemClass","InnCard","id","ABiI","type","DrugINN","name","Гентамицин + Фузидовая кислота","internationalName","Gentamycinum+ Acidum fusidicum","geotarId","2317","drugBankId","docAttachments",[],"clinRecCount","description","application","

Применение у детей

По 1-2 капли в ухо или в каждый носовой проход 3 раза в сутки.

Взрослые

По 2-5 капель в ухо или в каждый носовой проход 3 раза в сутки.

При хроническом тонзиллите используется 2-3 мл в 100-200 мл раствора 0,9 % хлорида натрия для промывания лакун при помощи шприца с длинной канюлей. Курс лечения составляет 4-15 дней.

","

Чувство жжения при нанесении на пораженные участки кожи и слизистых оболочек, аллергические реакции.

","

Перфорация барабанной перепонки, индивидуальная непереносимость.

","specialInstructions","

Следует избегать попадания препарата в глаза.

","interactions","

Не описано.

","overdose","

Случаи передозировки не описаны.

Лечение симптоматическое.

","actionMechanism","pharmacodynamic","

Комбинированный антибактериальный, противовоспалительный препарат для местного применения.

Гентамицин

Антибиотик из группы аминогликозидов. Связывается с 30S-субъединицей рибосом бактериальной клетки и нарушает движение рибосомы по нитям РHK. Также изменяет процессы считывания кода РHK, что приводит к синтезу функционально неактивных белков. Способен нарушать проницаемость цитоплазматической мембраны микроорганизмов. Имеет бактерицидный тип действия в отношении Neisseria gonorrhoeae, в том числе штаммов, продуцирующих пенициллиназу.

Фузидовая кислота

Антибиотик полициклической структуры. Нарушает синтез белка в микробной клетке, активен в отношении Bacteroides spp., Staphylococcus spp., особенно Staphylococcus aureus и Staphylococcus epidermidis (включая метициллин-резистентные штаммы), Neisseria spp., Streptococcus spp., Nocardia asteroides, Clostridium spp., Enterococcus spp., Mycobacterium tuberculosis, Mycobacterium leprae и Corynebacterium minutissimum.

","pharmacokinetic","

Средство для местного применения, практически не абсорбируется в кровоток и не оказывает системного действия.

","pregnancy","

Рекомендации по FDA - категория В. Не оказывает системного действия - применяется в период беременности и лактации.

","fertility","precautions","

Высокая индивидуальная чувствительность.

","indications","

Применяется для лечения гнойно-воспалительных заболеваний уха, носа и придаточных пазух: при отите, евстахиите, рините, синуситах, а также используется при хроническом тонзиллите. С профилактической целью применяется при оперативных вмешательствах на придаточных пазухах носа.

","drivingInstructions","icd10",[178,190,196,203,209,215,221,227,233,239],{"_179":180,"_144":181,"_142":182,"_183":180,"_138":184,"_140":185,"_186":187,"_188":189},"drugGeotarID","H60","Otitis externa","Наружный отит","drugICD10CodeShort","SDYw","DrugICD10","code","VIII(H60-H95).H60-H62.H60","level","3",{"_179":191,"_144":192,"_142":193,"_183":191,"_138":194,"_140":185,"_186":195,"_188":189},"H68","Eustachian salpingitis and obstruction","Воспаление и закупорка слуховой [евстахиевой] трубы","SDY4","VIII(H60-H95).H65-H75.H68",{"_179":197,"_144":198,"_142":199,"_183":197,"_138":200,"_140":185,"_186":201,"_188":202},"H93.9","Disorder of ear, unspecified","Болезнь уха неуточненная","SDkzLjk","VIII(H60-H95).H90-H95.H93.9","4",{"_179":204,"_144":205,"_142":206,"_183":204,"_138":207,"_140":185,"_186":208,"_188":189},"J00","Acute nasopharyngitis [common cold]","Острый назофарингит [насморк]","SjAw","X(J00-J99).J00-J06.J00",{"_179":210,"_144":211,"_142":212,"_183":210,"_138":213,"_140":185,"_186":214,"_188":189},"J01","Acute sinusitis","Острый синусит","SjAx","X(J00-J99).J00-J06.J01",{"_179":216,"_144":217,"_142":218,"_183":216,"_138":219,"_140":185,"_186":220,"_188":202},"J01.0","Acute maxillary sinusitis","Острый верхнечелюстной синусит","SjAxLjA","X(J00-J99).J00-J06.J01.0",{"_179":222,"_144":223,"_142":224,"_183":222,"_138":225,"_140":185,"_186":226,"_188":202},"J01.1","Acute frontal sinusitis","Острый фронтальный синусит","SjAxLjE","X(J00-J99).J00-J06.J01.1",{"_179":228,"_144":229,"_142":230,"_183":228,"_138":231,"_140":185,"_186":232,"_188":189},"J32","Chronic sinusitis","Хронический синусит","SjMy","X(J00-J99).J30-J39.J32",{"_179":234,"_144":235,"_142":236,"_183":234,"_138":237,"_140":185,"_186":238,"_188":202},"J35.0","Chronic tonsillitis","Хронический тонзиллит","SjM1LjA","X(J00-J99).J30-J39.J35.0",{"_179":240,"_144":241,"_142":242,"_183":240,"_138":243,"_140":185,"_186":244,"_188":245},"T80-T88","Complications of surgical and medical care, not elsewhere classified","ОСЛОЖНЕНИЯ ХИРУРГИЧЕСКИХ И ТЕРАПЕВТИЧЕСКИХ ВМЕШАТЕЛЬСТВ, НЕ КЛАССИФИЦИРОВАННЫЕ В ДРУГИХ РУБРИКАХ","VDgwLVQ4OA","XIX(S00-T98).T80-T88","2","atc",[248],{"_179":249,"_144":250,"_142":251,"_138":252,"_140":253,"_186":252,"_188":189},"D.06.C","Antibiotics And Chemotherapeutics, Combinations","Антибиотики в комбинации с противомикробными средствами","D06C","DrugATC","contraindicationsList",[256],{"_142":257,"_138":258,"_140":259,"_179":258},"Детский возраст до 6 мес","chld_6m","DrugPatientStatus","precautionsList","adverseEffectList",[],"pharmGroupList","

12.1 Антибиотики
12.1.1 Аминогликозиды

","substanceType","Непатентованное международное наименование","structure","[?] ","image",{"_38":271,"_272":8},"/images/substance-placeholder.jpg","isPlaceholder","esklp",{"_275":276,"_277":-5},"esklpList",[],"isInnVital","aggregatedEsklpGroups",[],"entityId","https://www.lsgeotar.ru/substances/gentamycinum-acidum-fusidicum-ABiI/interactions","substanceInteractions",{"_40":284,"_290":112,"_291":292,"_293":294},{"_285":286,"_287":70,"_288":112,"_289":-5},"query","","pageSize","page","filters","total","countedSignificances",[],"interactionList",[],"pages/PagesLayout","actionData","errors"]

Гентамицин + Фузидовая кислота (Gentamycinum+ Acidum fusidicum)