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Взрослым - 40-50 мг в сутки (4-5 таблеток), в течение 3-4 дней. Детям от 3 до 7 лет - 30 мг в сутки. Препарат применяют, медленно рассасывая во рту, через 15-30 минут после еды.

","adverseEffects","

Аллергические реакции, кожная сыпь.

","contraindications","

Гиперчувствительность, беременность.

","specialInstructions","

Амбазон действует только на бактерии, поэтому, если воспалительные заболевания полости рта, гортани или глотки вызваны вирусами или грибами, применение будет неэффективно.

","

Клинически значимые взаимодействия с другими препаратами не описаны.

В течение 3 ч после применения препарата воздерживаться от приема пищи и питья.

","overdose","

Не описана. Лечение симптоматическое.

","actionMechanism","pharmacodynamic","

Противомикробное и антисептическое средство. Связывание с ДНК, РНК, мембранами и белками бактерий, нарушение их синтеза. Обладает бактериостатическим действием. Эффективен в отношении Streptococcus haemolyticus, Streptococcus viridans, Pneumococcus. Применяют в виде таблеток для рассасывания при ангине, гингивите, фарингите, ларингите, стоматите; для профилактики инфекций полости рта в периоперационный период (тонзиллэктомия, удаление зуба).

","pharmacokinetic","

Оптимальная терапевтическая концентрация в слюне - на 3-4-й день приема в дозе 0,03-0,05 г в сутки.

","pregnancy","

Категория рекомендаций FDA не определена. Адекватные и хорошо контролируемые исследования на человеке и животных не проводились.

","fertility","precautions","

Доброкачественные и злокачественные новообразования.

","indications","

Профилактика и лечение острых инфекционно-воспалительных заболеваний полости рта и глотки: ангина, тонзиллит, стоматит, гингивит, фарингит; послеоперационное лечение при тонзиллэктомии и экстракции зубов.

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Амбазон (Ambazone)