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Гиперчувствительность к компонентам препарата.

","specialInstructions","Во время менструации лечение прерывать не следует. При грибковых заболеваниях влагалища рекомендуется одновременное лечение полового партнера. В период лечения следует избегать половых контактов.","При одновременном применении нистатина с клотримазолом активность последнего снижается. ","overdose","actionMechanism","pharmacodynamic","

Полиеновый противогрибковый антибиотик, высокоактивный в отношении дрожжеподобных грибов рода Candida. В структуре антибиотика имеются двойные связи, обладающие высокой тропностью к стероловым структурам цитоплазматической мембраны грибов, что способствует встраиванию молекулы препарата в мембрану клетки и образованию большого количества каналов, через которые осуществляется бесконтрольный транспорт электролитов; повышение осмолярности внутри клетки приводит к ее гибели. Толерантность развивается очень медленно.

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При назначении препарата необходимо сопоставлять пользу для матери и потенциальный риск для плода. Неизвестно, проникает ли препарат в грудное молоко, поэтому в период лактации следует отказаться от грудного вскармливания.

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Лечение и профилактика кандидоза слизистой оболочки влагалища.

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В одном суппозитории содержится: нистатин — 250 000 ЕД или 500 000 ЕД и вспомогательные вещества (бутилоксианизол для медицинских целей чистый, ионол пищевой (бутилокситолуол) или дибунол, кислота лимонная пищевая, масло вазелиновое, твердый жир, тип А или витепсол) — достаточное количество для получения суппозитория массой от 2,37 до 2,63 г.

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2 года. Не использовать препарат после истечения срока годности, указанного на упаковке.

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Список Б. В недоступном для детей месте, при температуре от 5 ⁰С до 20 ⁰С.

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Нистатин (Nystatin)